This study explores the macroeconomic impact of the Zero Over-Dimension Over-Load (ODOL) policy in Indonesia, especially its influence on logistics costs, inflation, and economic growth. The policy is not discussed here only as a matter of transport compliance, but also as a structural change in logistics governance that may affect the wider economy. A mixed-methods approach was used, based on primary survey data collected in 2025 from logistics stakeholders in DKI Jakarta and West Java. For the analysis, the Leontief Price Model was applied to estimate price transmission effects, while the dynamic Computable General Equilibrium (CGE) IndoTERM model was used to simulate cost shocks, investment adjustment, and fiscal reallocation. The findings show that the policy increases national logistics costs by 4.58% in the short term, which raises the logistics cost-to-GDP ratio to 14.94%. However, the longer-term results are more positive. The simulation suggests a 0.05% increase in GDP, equivalent to a net output gain of IDR 14.3 trillion. This result is associated with a 6.74% increase in fleet investment, estimated at IDR 42.4 trillion, as well as fiscal savings caused by lower infrastructure damage. These results suggest that stricter logistics regulation may bring broader economic benefits when the analysis goes beyond the immediate rise in transport costs. In practical terms, the policy should be supported by fiscal incentives for fleet modernization and by careful timing of enforcement, especially to limit inflationary pressure in food and construction-related sectors.