The intrinsic variability associated with waste-derived bitumen modifiers poses persistent limitations for conventional deterministic pavement design approaches. This study establishes a hybrid modelling architecture that integrates physics-informed boundary constraints with stochastic simulation components to predict the rheological performance of asphalt binders modified with waste frying oil. Literature-derived parameter ranges are embedded within a Gaussian copula-based dependency structure and expanded through large-scale Monte Carlo simulation to generate a statistically convergent dataset comprising 1,000,000 realizations. The integrated modelling structure preserves the nonlinear relationships among key rheological indicators, including penetration, softening point, and modifier dosage, while maintaining physical consistency. The predictive capability of the proposed architecture is validated using standard statistical metrics, achieving coefficients of determination exceeding 0.98 for penetration and 0.93 for softening point. A mode-based master curve is further constructed to provide a stable and computationally efficient representation of binder behaviour across varying modifier contents. The results demonstrate that the proposed hybrid modelling structure offers a reliable alternative to extensive laboratory testing, reducing experimental effort while retaining predictive fidelity. From a system perspective, the framework provides a structured basis for incorporating material variability into pavement performance evaluation and can be interpreted as a simplified digital twin component for asphalt material systems. The study thereby contributes to the integration of stochastic modelling within engineering-oriented predictive structures for sustainable pavement design.
High-entropy alloys (HEAs) exhibit high mechanical strength, phase stability, and damage tolerance, making them promising materials for advanced structural applications. However, reliable prediction of their mechanical response and microstructural failure remains challenging because alloy composition, phase constitution, grain characteristics, thermodynamic descriptors, and deformation behaviour are strongly coupled. This study investigates a physics-guided hybrid modelling framework that integrates physically meaningful alloy descriptors with Transformer-based representation learning for failure and mechanical response prediction in HEAs. Mixing entropy, atomic size mismatch, valence electron concentration, phase stability parameters, and microstructural and mechanical descriptors were incorporated into the data-driven modelling architecture to establish physically informed relationships between material characteristics and failure behaviour. The developed framework was used to predict ultimate tensile strength (UTS), failure strain, stress–strain response, and microstructural failure probability. The results showed close agreement between the predicted and measured UTS and failure strain and demonstrated higher $R^2$ values than random forest, extreme gradient boosting (XGBoost), convolutional neural network (CNN), long short-term memory (LSTM), and standard Transformer models. The predicted stress–strain curves also reproduced the principal deformation behaviour observed in the experimental data. Failure-probability mapping and attention analysis identified the material and microstructural features associated with failure, while the ablation study showed that incorporating physics-guided information improved predictive accuracy, reliability, and interpretability. These findings demonstrate that the structured integration of physics-based descriptors and Transformer learning provides an effective hybrid modelling strategy for relating material constitution to mechanical response and failure. The proposed framework provides a physically informed and interpretable approach to failure prediction and data-assisted design of HEAs and offers a transferable modelling strategy for intelligent engineering analysis of complex material systems.